Today’s biggest pre-market stock moves: 10 biggest gains and losses on Wednesday

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Stock moving news this morning includes earnings reports, clinical trial data, new analyst coverage and more.

Let’s get to that news below!

Pre-market stock moves: Top 10 gainers

1. Sunshine Biopharma (NASDAQ:SBFM) shares skyrocket by more than 206% as heavy trading sends shares higher this morning.
2. Direct Digital Shares (NASDAQ:DRCT) shares gain over 83% following reports from an analyst who begins covering the stock.
3. TC BioPharm (NASDAQ:TCBP) shares rise nearly 41% after the announcement of positive data from phase 1b/2a clinical trials.
4. American rebel holdings (NASDAQ:AREB) shares are up more than 33% after falling 12.9% on Tuesday.
5. Kiromic BioPharma (NASDAQ:KRBP) shares of other biopharmaceutical companies are up more than 32% today.
6. ECMOHO (NASDAQ:MOHO) shares up over 31% amid heavy trading in penny stocks.
7. Ecoark Holdings Company (NASDAQ:FRUIT SKIN) the company’s shares surged more than 29% after revealing an update on progress on its latest oil well.
8. Babble (NASDAQ:BMBL) the company’s stock jumped over 23% with the release of its fourth quarter 2021 earnings report.
9. A new lifestyle (NASDAQ:NVFY) shares gain almost 21% despite no news this morning.
10. TDH Holding (NASDAQ:PETZ) shares surged almost 20% as the stock saw massive trading volume this morning.

Top 10 Losers

1. Circuit (NASDAQ:CRCT) the company’s stock falls nearly 32% with the release of its Q4 2021 earnings report.
2. Text (NYSE:YES) shares fall more than 26% with Q4 earnings and news that the CEO and CFO are stepping down.
3. Hycroft Mining Holding (NASDAQ:HYMC) company shares fell by over 23% after Tuesday’s increase in metal prices.
4. Stitch correction (NASDAQ:FIX) shares fall more than 23% with the release of the second quarter 2022 earnings report.
5. CYRENE (NASDAQ:CYRN) shares are down more than 16% after late gains yesterday on no news.
6. Environmental Cypress (NYSE:CELP) shares are down almost 16%, continuing the negative move from yesterday.
7. Big Panther Mining (NYSEAMERICAN:GPL) shares fell more than 15% after Tuesday’s gain.
8. Ocean Pal (NASDAQ:OP) shares are down more than 15% after yesterday’s rally against other penny stocks.
9. PoliMet mining (NYSEAMERICAN:PLM) after Tuesday’s increase, the company’s shares fell by over 14%.
10. Royal mess (NYSE:MTR) shares close our pre-opening changes down more than 14%.

On the date of publication William Whitedid not hold (directly or indirectly) any positions in the securities mentioned in this article. The opinions expressed in this article are those of the author and are subject to InvestorPlace.com Publishing guidelines.